Champions Manchester City kick start their title defence away to Arsenal in an explosive start to the new 2018/19 season.
New Gunners boss Unai Emery is presented with a tough start at home to last season’s runaway winners, with Pep Guardiola’s men backed by the bookies as the favourites to win the Premier League again.
Manchester United will entertain 2015/16 champions Leicester at Old Trafford on the opening day of the new campaign on August 11.
Last season’s beaten Champions League finalists Liverpool welcome West Ham and their new manager Manuel Pellegrini to Anfield first up.
Marco Silva will get his Everton reign up and running with a visit to newly-promoted Wolves at Molineux.
Fellow new boys Cardiff travel to Bournemouth, while play-off winners Fulham entertain London rivals Crystal Palace at Craven Cottage.
Huddersfield clinched survival last May by holding Chelsea to a draw at Stamford Bridge. And David Wagner’s men will start their season at home to the Blues.
Tottenham, meanwhile, travel to Newcastle again on the opening day – just as they did last year, where they won 2-0.
Spurs have their new stadium to look forward to. And it Liverpool who will be the first visitors to the new White Hart Lane on September 15 with Mauricio Pochettino’s side returning to Wembley for their August 18 home game against Fulham.