Premier League champions Liverpool will play FA Cup winners Crystal Palace in the fourth round of the Carabao Cup.
Liverpool, a record 10-time winners of the League Cup, needed a late goal to beat Southampton, while Palace were taken to penalties by Millwall.
Holders Newcastle United host Tottenham in another all-Premier League tie while Arsenal, who have not won the competition since 1993, face Brighton.
Grimsby Town, the only League Two side still standing and conquerors of Manchester United, get another home tie against Premier League Brentford.
And with three Welsh sides in the last 16 for the first time, it was perhaps inevitable there would be an all-Welsh clash as Wrexham host Cardiff City, with 2013 winners Swansea handed a tie against Manchester City.
Full Carabao Cup draw for fourth round
Arsenal v Brighton
Grimsby Town v Brentford
Swansea City v Manchester City
Newcastle United v Tottenham
Wrexham v Cardiff City
Liverpool v Crystal Palace
Wolves v Chelsea
Wycombe v Fulham
Ties to be played in the week of 27 October
(BBC Sport)
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